{"id":3038,"date":"2017-03-24T21:00:00","date_gmt":"2017-03-24T18:00:00","guid":{"rendered":"https:\/\/neolife.com.tr\/a-new-imaging-method-for-prostate-cancer-ga-68-psma-petct\/"},"modified":"2021-11-30T16:11:50","modified_gmt":"2021-11-30T13:11:50","slug":"a-new-imaging-method-for-prostate-cancer-ga-68-psma-petct","status":"publish","type":"post","link":"https:\/\/www.neolife.com.tr\/en\/a-new-imaging-method-for-prostate-cancer-ga-68-psma-petct\/","title":{"rendered":"A NEW IMAGING METHOD FOR PROSTATE CANCER, Ga-68 PSMA PET\/CT"},"content":{"rendered":"<h2>A NEW IMAGING METHOD FOR PROSTATE CANCER<\/h2>\n<p><a href=\"https:\/\/neolife.com.tr\/en\/prostate-cancer\/\">Prostate cancer<\/a> is the most common type of cancer in male subjects and it is the second most common cause of death, following cancer, in developed countries.<\/p>\n<p>Radical prostatectomy and radiotherapy is the first-line treatment for prostate cancer that is confined to the prostate gland. Selection of treatment is based on the extent the tumor spread.<\/p>\n<p>Cross-sectional imaging studies, such as computed tomography (CT) and Magnetic Resonance Imaging (MRI), and functional imaging studies, such as F-18 FDG PET, F18 Choline PET and Ga-68 PSMA, contribute to ability of visualizing metastatic foci.<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_1758\" style=\"width: 1216px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" aria-describedby=\"caption-attachment-1758\" class=\"wp-image-1760 size-full\" src=\"https:\/\/neolife.com.tr\/wp-content\/uploads\/2017\/03\/Ga-68-PSMA-PET-BT.jpg\" alt=\"Ga-68 PSMA PET\/BT\" width=\"1206\" height=\"416\" \/><p id=\"caption-attachment-1758\" class=\"wp-caption-text\">Ga-68 PSMA PET\/BT<\/p><\/div>\n<p>Elevated PSA in patients, who have undergone surgery, is referred as \u201cbiochemical recurrence\u201d that is witnessed in approximately 15-40% of patients. Guidelines issued by European Association of Urology defines biochemical recurrence as PSA reading = 0.2 ng\/ml in postoperative period and &gt;2 ng\/ml after radiotherapy.<\/p>\n<p>Existence of metastasis after recurrence is the principal factor that determines the selection of treatment. If there is no metastasis and salvage therapies are available, systemic treatment is given.<\/p>\n<div id=\"attachment_1762\" style=\"width: 1216px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" aria-describedby=\"caption-attachment-1762\" class=\"size-full wp-image-1767\" src=\"https:\/\/neolife.com.tr\/wp-content\/uploads\/2017\/03\/Neolife-Ga-68-PSMA-PET-BT.jpg\" alt=\"Ga-68-PSMA-PET-BT\" width=\"1206\" height=\"296\" \/><p id=\"caption-attachment-1762\" class=\"wp-caption-text\">Ga-68 PSMA PET\/BT<\/p><\/div>\n<p>PSMA is a surface antigen that is found in 95% of prostate cancer cells. Risk of metastasis or recurrence increases in aggressive tumors.<\/p>\n<p>Studies conducted on radionuclide-labeled peptides (PMSA), also known as Ga-68, show that this method is more accurate for visualizing recurrences and metastases of prostate cancer in comparison with other imaging methods.<\/p>\n<p>The higher PSA level, the higher the positivity rate of the test. For example, positivity rate of the test is 47.1% and 96.8% for PSA level below 0.2 ng\/ml and above 2 ng\/ml, respectively.<\/p>\n<h2>How is Ga-68 PSMA PET\/CT scanned?<\/h2>\n<ul>\n<li>PSMA is added to a radioactive substance, known as Ga-68, in a specific working environment. Ga-68 PSMA binds to PSMA antigen that are found in prostate cancer cells and makes them tumor cells visible.<\/li>\n<li>PSMA labeled with Ga-68 is intravenously administered.<\/li>\n<li>After 45 to 60 minutes elapse, whole body is scanned with PET\/CT device. The procedure lasts approximately for 30-40 minutes.<\/li>\n<li>The patient swallows contrast agent before the procedure. No extra preparation is required.<\/li>\n<li>Dose of radiation exposed is within acceptable limits and isolation is not required for patients. It is only necessary to stay away from pregnant women in same day.<\/li>\n<\/ul>\n<h2>Lu-177 PSMA for PROSTATE CANCER;<\/h2>\n<p>Ga-68 PSMA PET\/CT enables selection of patients who are eligible for radionuclide therapy (theranostics), such as Lu-177 (Lutetium 177).<\/p>\n<p>Patients with tumor that show uptake Ga-68 PSMA and can be visualized on PET\/CT scan are eligible for Lu-177. The smart molecule of PSMA binds to Lu-177 rather than Ga-68 and it is intravenously injected. Lu-177 uptake is absorbed by tumor cells that are ablated with Beta rays emitted.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\n","protected":false},"excerpt":{"rendered":"<p>Ga-68 PSMA PET\/CT is a new generation application used in the diagnosis and treatment of prostate cancer. It is used for diagnosis<\/p>\n","protected":false},"author":3,"featured_media":928,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[239,252],"tags":[],"class_list":["post-3038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-articles","category-saglik-yazilari-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A NEW IMAGING METHOD FOR PROSTATE CANCER, Ga-68 PSMA PET\/CT - Neolife T\u0131p Merkezi<\/title>\n<meta name=\"description\" content=\"Ga-68 PSMA PET\/CT is a new generation application used in the diagnosis and treatment of prostate cancer. 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