Cancer is preventable and treatable with early diagnosis. Although cancer is mostly the result of mutations that accumulate over a lifetime, a significant proportion of it is inherited. This means that if a blood relative has cancer, you may be a carrier. To find out this risk, it is possible to examine cancer risk genes identified in scientific articles and medical protocols. With the new generation sequencing technology of familial cancer screening, a tube of blood is enough to get this information. Hereditary Cancer Panels are used for this process.
| Test Adı | İncelenen Bölgeler |
|---|---|
| Comprehensive Hereditary Cancer Panel | 523 gene DNA SNVs, small in/dels, 59 CNV amp/dels, 23 Translocations |
| Comprehensive Hereditary Breast and Ovarian Cancer Panel | ATM, BARD1, BRIP1, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53,BRCA1,BRCA2 |
| Comprehensive Inherited Colorectal Cancer Panel | APC, MUTYH, MLH1, MSH2, MSH6, PMS1, PMS2, EPCAM, BMPR1A, SMAD4, STK11, PTEN, TP53, AXIN2, CDH1, CHEK2, GREM1, MSH3, NTHL1, POLD1, POLE |
| Hereditary Breast and Ovarian Cancer Panel | BRCA1, BRCA2 & MPLA |
| Hereditary Colorectal Cancer Biomarker | MLH1 |